Case Studies in Modern Drug Discovery and Development

41TyvDZhYPL

By

  • Xianhai Huang, PhD,  Principal Scientist at Merck Research Laboratories
  • Robert G. Aslanian, PhD, Professor of chemistry at William Paterson University , Senior Director of Medicinal Chemistry with the Schering-Plough Research Institute and Merck Research Laboratories.

Description

Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and development efforts, enabling medicinal chemists and pharmaceutical scientists to learn from actual examples. Each case study focuses on a particular drug and therapeutic target, guiding readers through the drug discovery and development process, including drug design rationale, structure-activity relationships, pharmacology, drug metabolism, biology, and clinical studies.

Improving the success rate of the drug discovery and development process is paramount to the pharmaceutical industry. With this book as their guide, readers can learn from both successful and unsuccessful efforts in order to apply tested and proven science and technologies that increase the probability of success for new drug discovery and development projects.

Key features

  • Puts into perspective the underlying issues facing the pharmaceutical industry and provides insight into future research opportunities.
  • Examining all phases of drug discovery and development from initial idea to commercialization
  • Examining some of today’s most important and life-saving medications
  • Examining drugs designed for different therapeutic areas such as cardiovascular disease, infection, inflammation, cancer, metabolic syndrome, and allergies
  • Examining examples of prodrugs and inhaled drugs
  • Examining reasons why certain drugs failed to advance to market despite major research investments

Review

“This book will enrich the collection of medicinal chemists or pharmacologists involved in active drug discovery research, as well as students with a passion for pursuing a career in drug discovery.”  (Doody’s, 22 February 2013)

“A well-made glossary is available in the appendix, which defines the dozens of terms that a medicinal chemist will encounter in his/her career. . . This book demonstrates yet again the need for new, better medicines and the reasons for the high cost of drug research. An enjoyable read!.”  (ChemMedChem, 1 January 2013)

Book details

  • Publisher: Wiley; 1 edition (June 5, 2012)
  • Language: English
  • ISBN-10: 0470601817
  • ISBN-13: 978-047060181

Download

This content is for gold members only. Log In or Register to see

Incoming search terms:

Tags: , , , , , , ,

Comments are closed.