Drug Disposition and Pharmacokinetics: From Principles to Applications


Stephen H. Curry, Professor of Pharmacology and Physiology, University of Rochester, USA
Robin Whelpton, Senior Lecturer, Queen Mary University of London, UK


This is an authoritative, comprehensive book on the fate of drug molecules in the body, including implications for pharmacological and clinical effects. The text provides a unique, balanced approach, examining the specific physical and biological factors affecting the absorption, distribution, metabolism and excretion of drugs, together with mathematical assessment of the concentrations in plasma and body fluids. Understanding the equations requires little more than a basic knowledge of algebra, laws of indices and logarithms, and very simple calculus. A companion web site contains additional illustrations, further equations and numerous worked examples.
Whilst this book has its roots in the highly acclaimed book of the same name, written by Stephen Curry nearly thirty years ago, it is essentially a new book having been restructured and largely rewritten. This readable and informative book is an invaluable resource for professionals and students needing to develop a rational approach to the investigation and application of drugs.

Key features

  • A vigorous, balanced account of the processes underlying drug disposition and the practical uses of pharmacokinetic derivations.
  • Generously illustrated with examples, tables and figures.
  • Written by two experienced authors with a proven track record in research, teaching and industry.

Book details

  • Publisher: Wiley; 1 edition (December 1, 2010)
  • Language: English
  • ISBN-10: 0470684461
  • ISBN-13: 978-0470684467


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