High-Throughput Analysis in the Pharmaceutical Industry (Critical Reviews in Combinatorial Chemistry)


Perry G. Wang


The introduction of combinatorial chemistry technology has increased the amount of compounds generated in a year from 50 to 2000. Conventional analytical approaches simply cannot keep up. These circumstances have caused drug discovery to take on the shape of a bottleneck, like traffic through a toll booth. In order to break the bottleneck, a corresponding revolutionary improvement to the conventional methodology must happen.

Key features

  • Examines the important role high-throughput analysis  plays in successful drug discovery and development
  • Describes the development and application of the state-of-the-art technologies
  • Covers drug discovery including pharmacokinetics and metabolism
  • Provides a systematic description of high-throughput analysis for the pharmaceutical industry
  • Presents advanced instrumentation and automation methods for drug analysis
  • Includes practical examples of new analytical technologies in the drug discovery and development

Book details

  • Series: Critical Reviews in Combinatorial Chemistry (Book 4)
  • Hardcover: 432 pages
  • Publisher: CRC Press (August 20, 2008)
  • Language: English
  • ISBN-10: 142005953X
  • ISBN-13: 978-1420059533


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